We have a near-12/1 acca to get behind for our opening Serie A betting tips of the 2025/26 season.
The BOYLE Sports mantra is Back Yourself when it comes to having a wager, and hopefully, there will be some useful pointers for punters to consider here.
Who Will Win Serie A 2025/26?
Serie A Betting Tips & Predictions – 11/1+ ACCA
23/20 Tip #1
Fiorentina to win at Cagliari at 23/20
Fiorentina suffered only one defeat in their opening 14 Serie A matches last season, winning nine, and we think they could get off to another strong start this term. The Viola, who have the hugely experienced Stefano Pioli back in charge, have an impressive recent record against the Sardinian club, winning each of the last four meetings between the two and six of nine matches since Cagliari last tasted success back in 2019, and they can be backed at 23/20 to add another win to that tally on Saturday.
Fiorentina have also retained the services of Moise Kean - second in the Serie A scoring charts last season - and he can be backed at 5/1 to be the first goalscorer.
1/3 Tip #2
AC Milan to beat Cremonese at 1/3
AC Milan had to settle for a disappointing eighth-placed finish last season, but they looked a side on the up towards the end of the campaign, winning five of their last seven league games and reaching the Coppa Italia final. They also started this season with a cup win over Bari and and we expect them to be too strong for a promoted Cremonese side who squeezed up through the play-offs.
Milan have lost the likes of Tijjani Reijnders, Malick Thiaw and Theo Hernandez this summer but have invested in rising talent and also brought in veteran playmaker Luka Modric on a free, with the hope they will be in stronger place overall.
1/3 Tip #3
Como to draw with Lazio at 9/4
Only Atalanta won more away matches in Serie A last season than Lazio, and among their victims were champions Napoli and a promoted Como side who were crushed 5-1 in front of their own fans. However, that was just a few months into Como's first Serie A campaign in 21 years, and we think Cesc Fabregas' men - who ended up finishing 10th last term - will prove a different proposition this time around.
A busy summer, which has seen the arrivals of a host of new faces including Alvaro Morata, Jesus Rodriguez and Nicolas Kuhn, should see Como claim at least a point against the Romans.
9/4 Tip #4
Atalanta to win against Pisa and both teams to score at 9/4
Atalanta have been a fixture near the top of the Serie A standings for the last nine seasons, finishing third on four occasions, including last term, but they head into the new campaign under a cloud of uncertainty. They've lost long-serving coach Gian Piero Gasperini to Roma, with former Southampton boss Ivan Juric taking the reins seen Serie A's leading marksman last term, Mateo Retegui, move to Saudi Arabia, and there are doubts about the future of influential forward Ademola Lookman too.
However, we are still backing them to overcome promoted Pisa in their 2025/26 season opener. Both teams were second top-scorers in their respective divisions last term, so know where the goal is and we also think they could both net this weekend.
Atalanta Win & BTTS vs Pisa @ 9/4
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