Manchester City and Liverpool are used to high-pressure encounters but this season's first meeting feels a little different with Arsenal setting such a strong pace at the top of the table.
There may only be 10 games gone but with these teams six and seven points adrift of the Gunners respectively, neither would be fully satisfied with a share of the spoils.
That scenario makes 21/20 for both sides to score and no draw an appealing price for our initial Man City vs Liverpool prediction.
Man City vs Liverpool Preview – Premier League 2025/26
How to Watch
How to watch Man City vs Liverpool
Sunday's blockbuster battle is scheduled to kick off at 16:30 GMT and will be broadcast live on Sky Sports Main Event.
Head-to-Head Record
Man City vs Liverpool head-to-head record
Liverpool took advantage of City being below par last term, securing 2-0 victories at Anfield and Etihad Stadium.
That evened things up over the past 16 league meetings, which have yielded five wins apiece and six draws.
Mohamed Salah is predictably the player with the best scoring record in this fixture, incredibly netting in 13 of the last 21 encounters in all competitions.
The winger has not been at his prolific best this season, but 15/8 for Salah to strike at any time still stands out from the Man City vs Liverpool odds.
Man City Form Guide
Manchester City form guide
Pep Guardiola's side looked set for another tricky campaign when losing to Tottenham and Brighton early on but have only tasted defeat once in 13 subsequent outings.
Wednesday's 4-1 Champions League victory over Borussia Dortmund made it six wins out of seven.
Guardiola accepts Arsenal have raised the bar so far this term but clearly believes City are capable of challenging for top spot.
He said: "The season is long, so we try to be there and see what happens. To be honest, I'm so excited and happy to prepare for Sunday. I'm desperate to play against Liverpool and we'll see what happens."
Phil Foden should be full of confidence after bagging a brace against Dortmund in midweek and 2/1 for him to net again here is tempting.
Liverpool Form Guide
Liverpool form guide
Arne Slot is also back in good spirits after seeing his side recover from a run of six defeats in seven outings by claiming back-to-back victories.
Aston Villa were beaten 2-0 in the Premier League before Tuesday's 1-0 triumph over Real Madrid provided yet another magnificent Anfield atmosphere in Europe.
The most significant aspect of their win over Real was arguably not the result but the nature of the performance, being the better team throughout.
"Impressive because we played against an incredible side that is in an unbelievable run of form, only lost once, won all the other games," said Slot.
"If you can win against them, but also put in the performance we had, that is very positive."
Conor Bradley produced a fine display to come out on top in a fascinating battle with Vinicius Junior but the feisty 22-year-old full-back will be put under plenty of pressure again here.
The Northern Irishman had a run of five yellow cards in eight games earlier this season and 5/4 for Bradley to be booked on Sunday is added to our Man City vs Liverpool betting tips.
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