The opening NFL London game of 2026 comes at a nice time for the Washington Commanders and the Indianapolis Colts , who both picked up their first wins of the season last week. A scrappy 19-17 success over the Houston Texans saw Indianapolis end a nine-match losing streak stretching back to last November, but Washington’s 33-31 triumph over Super Bowl champions the Seattle Seahawks was surely more noteworthy.
That performance makes Sunday’s designated ‘home’ team hard to resist at 10/11 with 3.5 points start for our initial Washington Commanders vs Indianapolis Colts prediction.
How to Watch
How to watch Washington Commanders vs Indianapolis Colts
Sunday’s Tottenham Hotspur Stadium clash is scheduled to kick off at 14:30 BST and will be broadcast live on Channel 5 and Sky Sports NFL .
Head-to-Head
Washington Commanders vs Indianapolis Colts head-to-head record
These teams are infrequent rivals, with Washington coming out on top 17-16 when they last met four years ago , but Indianapolis previously enjoying four straight wins between 2006 and 2018.
Form Guides
Washington Commanders form guide
There was a lot to like about the way Washington’s revamped defence performed in an opening 24-22 loss at the Philadelphia Eagles , but they found life tough in that department during a 37-20 away defeat against the Dallas Cowboys . The fact that quarterback Jayden Daniels sustained a dislocated elbow in that game made things look bleak, but the Commanders showed great spirit when bouncing back with a surprise success against Seattle , who had won a dozen games in a row.
Turnovers played a part in that upset win, with Kain Medrano collecting one of Sam Darnold’s two interceptions and sprinting back 50 yards for a pick six. However, back-up QB Marcus Mariota deserves most of the credit for throwing three touchdown passes, as star wide receiver Terry McLaurin and high-profile free agency capture Stefon Diggs continued a strong start to the season.
With impressive first-round draft pick Sonny Styles helping to establish a change of culture on defence, even doubts about Daniels returning from injury in London don’t put us off the Commanders. McLaurin caught six passes for 77 yards and a TD against Seattle’s much-feared secondary, so 5/6 for him to have over 52.5 receiving yards here stands out from the Washington Commanders vs Indianapolis Colts player props.
Indianapolis Colts form guide
The Colts infamously fell from 8-2 to 8-9 last term following an injury to QB Daniel Jones and even though he has been back healthy this season, it hasn’t been the most convincing comeback. Indianapolis just about did enough to edge out a struggling Houston outfit, going ahead for good via a 53-yard field goal in the final two minutes of that match.
That contest desperately lacked sparkle, though, and Jones was guilty of giving away an interception for the third straight game , having previously been picked off in a 41-23 home loss to the Baltimore Ravens and a 33-30 overtime defeat at the Kansas City Chiefs . Admittedly, that was a brave effort at Arrowhead Stadium, but it ended with a double blow, as the narrow loss was compounded by an injury to top wide receiver Alec Pierce , who remains sidelined.
Washington will no doubt go all out to stop star running back Jonathan Taylor and then put pressure on Jones when he goes to the air, so 6/5 for him to throw at least one more interception in London is added to our Commanders vs Colts betting tips.
Betting Tips
Washington Commanders vs Indianapolis Colts Betting Tips
Washington Commanders to win with 3.5 points start @ 10/11
Terry McLaurin to to have over 54.5 receiving yards @ 5/6
Daniel Jones to throw at least one interception @ 6/5
*Prices subject to fluctuation
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