NFL Divisional Round Predictions, Betting Tips & Odds – 4 Playoffs Best Bets

BOYLE Sports Team 16 January 2026 at 08:59pm
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As the race to reach Super Bowl LX hots up, we’ve got NFL Divisional Round predictions for all four of this weekend’s matches and will land a near-10/1 acca if they are successful.

BOYLE Sports have great odds on the top gridiron games and don’t forget the early payout offer on straight match result bets if your team goes 17 points ahead at any point.

That concession certainly came in handy during the Wild Card Weekend , when our selection Green Bay Packers blew a 21-3 lead in Chicago Bears but punters still collected.

NFL Divisional Round Predictions – Playoffs Tips

Denver vs Buffalo Tip

Denver To Beat Buffalo @ 20/23

Josh Allen put in a heroic performance when carrying the Buffalo Bills to a 27-24 victory at Jacksonville Jaguars but the Jaguars also contributed to their own downfall, giving away two interceptions and a red-zone turnover on downs.

Following up such a titanic tussle, when the lead changed hands four times in the fourth quarter alone, with another tough road trip to the imposing Mile High Stadium will be so hard, especially as Denver Broncos’ dominant defence has had a week off to freshen up.

The Broncos have only lost once at home this season and have everything in their favour here.

5/6
● LIVE ODDS Denver Broncos Match Betting

Seattle vs San Francisco Tip

Seattle -7.5 Points To Beat San Francisco @ 20/21

The San Francisco 49ers ended the reign of Super Bowl champions Philadelphia Eagles but that 23-19 away win came at a cost, with star tight end George Kittle suffering a season-ending injury that will hurt them here.

The Seattle Seahawks’ swarming defence shut down San Francisco in a 13-3 triumph just two weeks ago that wrapped up the NFC West division and earned them the top seed in this conference.

The Seahawks were also able to control proceedings that day due to a strong running game, with Kenneth Walker III rushing for 97 yards, and a repeat performance should see them wear down the 49ers with room to spare.

1/1
● LIVE ODDS Seattle Seahawks Handicap Betting

New England vs Houston Tip

New England To Beat Houston @ 8/15

This is expected to be a defensive battle in testing conditions, as the New England Patriots racked up six sacks in last week’s 16-3 defeat of the Los Angeles Chargers and Houston Texans put Aaron Rodgers on the floor four times during a 30-6 rout of the Pittsburgh Steelers .

That means it could come down to which young quarterback holds their nerve best and that is where the Patriots have a clear edge.

Drake Maye was streets ahead of his opposite number during the regular season and although he wasn’t at his polished best in the Wild Card round, he was still far more convincing than CJ Stroud , who was quite simply all over the place until the Texans finally pulled clear in the fourth quarter.

8/15
● LIVE ODDS New England Patriots Match Betting

Chicago vs Los Angeles

Los Angeles Rams -4.5 Points To Beat Chicago @ 10/11

The Los Angeles Rams had to survive a big scare in Carolina Panthers , where Matthew Stafford found Colby Parkinson for a touchdown with 38 seconds remaining to give them a 34-31 victory over the Panthers .

However, that felt more like a bump in the road than a meltdown, as Los Angeles were hit hard by penalties after being very disciplined during the regular season, while a late blocked punt also hurt them.

Back on home turf, where they are 7-1 this term, the Rams can regroup and get their formidable offence back in top gear against a Chicago Bears outfit which pulled off another great escape when overturning an 18-point deficit versus Green Bay but just look in too deep at this level.

5/6
● LIVE ODDS Los Angeles Rams -3.5 Handicap Betting +3.5

Betting Tips

NFL Divisional Round Betting Tips

Denver Broncos To Beat Buffalo Bills @ 20/23

Seattle Seahawks -7.5 Points To Beat San Francisco 49ers @ 20/21

New England Patriots To Beat Houston Texans @ 8/15

Los Angeles Rams -4.5 Points To Beat Chicago Bears @ 10/11

Simply click/tap on the above betting tips to add to your betslip.

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