England have never been hotter favourites for a game against Wales than they are in this season’s opening round of Six Nations fixtures at Twickenham.
Steve Borthwick’s side are on an 11-match winning run which includes an incredible 68-14 rout of the same opponents in Cardiff last March.
The hosts should go into this contest full of confidence and ready to attack at every opportunity, which makes 4/7 for the first scoring play to be an England try hard to resist.
In previous years, a penalty for either side would feature prominently in this market, but with Wales in such disarray, England are expected to pass up an early shot at goal in favour of pushing for at least a five-pointer.
Betting Odds
England vs Wales Betting Odds – Six Nations 2026
Result | Odds | Chance |
England | 1/500 | 99.8% |
Wales | 20/1 | 4.8% |
Draw | 50/1 | 2.0% |
England are overwhelming favourites at 1/500, with Wales priced at 20/1, while the draw is available at 50/1, pointing to a one-sided contest in the betting.
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England vs Wales Prediction – Six Nations
Handicap Betting
England -28 @ 10/11
Wales +28 @ 10/11
Handicap Draw (-28) @ 18/
Total Points Betting
Over 53.5 Points @ 10/11
Under 53.5 Points @ 4/5
Try Scorer Betting
Try Scorer Betting Odds
Player | First Try Scorer | Anytime Try |
|---|---|---|
Henry Arundell | 6/1 | 4/7 |
Immanuel Feyi-Waboso | 6/1 | 4/7 |
Tommy Freeman | 8/1 | 5/6 |
Jamie George | 10/1 | 11/10 |
Alex Mitchell | 12/1 | 11/8 |
Bar | 14/1 | 13/8 |
With England expected to dominate territory and possession at Twickenham , the hosts’ back three are well placed to capitalise out wide, making Henry Arundell the headline option in the first try scorer market.
How to Watch
How to watch England vs Wales
The final game of the opening round of Six Nations fixtures is scheduled to kick off at 16:40 GMT on Saturday and will be broadcast live by ITV 1.
Irish viewers can tune into the game on RTÉ2 and RTÉ Player.
Head-to-Head
England vs Wales head-to-head record
England have won four straight encounters between these teams in this competition and last lost a Twickenham clash with Wales during the 2015 World Cup.
Winning margins have tended to be tight, with England prevailing by four, six, three, four and just two points in the last five Six Nations meetings at this venue.
However, Wales have never been in worse shape and it is 10/11 for a home win by at least 30 in the main handicap market among the England vs Wales odds.
Team News
Team News
England – Starting XV
Freddie Steward, Immanuel Feyi-Waboso, Tommy Freeman, Fraser Dingwall, Henry Arundell, George Ford, Alex Mitchell, Ellis Genge, Jamie George (c), Joe Heyes, Alex Coles, Ollie Chessum, Guy Pepper, Sam Underhill, Ben Earl
Replacements: Luke Cowan-Dickie, Bevan Rodd, Trevor Davison, Maro Itoje, Tom Curry, Henry Pollock, Ben Spencer, Marcus Smith
England have named a settled side early in the week, with Maro Itoje among the replacements to end his run of playing every minute of 30 consecutive Six Nations matches since 2020 . Fraser Dingwall and Tommy Freeman start in the centres, while Henry Arundell makes his first start since the 2023 Rugby World Cup.
Wales – Starting XV
Louis Rees-Zammit, Ellis Mee, Eddie James, Ben Thomas, Josh Adams, Dan Edwards, Tomos Williams, Nicky Smith, Dewi Lake (c), Archie Griffin, Dafydd Jenkins, Adam Beard, Alex Mann, Josh Macleod, Aaron Wainwright
Replacements: Liam Belcher, Rhys Carre, Tomas Francis, Ben Carter, Taine Plumtree, Harri Deaves, Kieran Hardy, Mason Grady
For Wales , Louis Rees-Zammit shifts to full-back in line with his club role at Bristol, Josh Macleod returns after injury, and Tomas Francis is recalled for his first cap since the 2023 Rugby World Cup.
Form Guides
Team Form Guides
England Form guide
England head into this year’s tournament as second favourites to seize France’s crown after being runners-up last term, when recovering from an opening 27-22 loss in Ireland to register four wins.
It was incredibly tense as Les Bleus were edged out 26-25 at Twickenham and then Scotland were only shaded 16-15 at this venue.
However, Borthwick’s men cut loose with a 47-24 triumph over Italy before that record-breaking victory in Cardiff.
England maintained the momentum with two summer successes in Argentina and beat the Pumas, Australia, Fiji and New Zealand during the autumn internationals.
Tommy Freeman scored in every Six Nations match last season and has been in fine form for Northampton this term, crossing the whitewash 11 times in nine appearances.
Let’s go with the powerful back to touch down in the first half of this match at 12/5 in our England vs Wales betting tips.
Wales Form guide
Wales kicked off last year with a 43-0 thrashing by France in Paris and went on to finish bottom of the table for a second successive time.
They did pick up three bonus points after performing with credit against Italy, Ireland and Scotland, but England put them to the sword in that closing encounter to make it 11 consecutive Six Nations defeats.
The autumn internationals featured a welcome 24-23 win over Japan but Wales conceded 177 points in heavy losses to Argentina, New Zealand and South Africa.
Head coach Steve Tandy has the almost impossible task of trying to lift a squad which has also been rocked by a domestic crisis at club level.
Pride and passion may keep it close for a while, but England should have far too much firepower as the game progresses.
England flanker Henry Pollock announced himself in the Test arena with two tries on debut against Wales last term and all five of his caps have been won as a dynamic and high-energy reinforcement off the bench.
The 21-year-old continues in that role for Saturday’s tussle and 5/1 for him to be the last tryscorer is another England vs Wales prediction.
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